Ugly Betty (2006-2010)

Ugly is the new beautiful.

Wannabe writer Betty Suarez is a plain girl from Queens, who is smart, hardworking and savvy but lacks a fashionable sense of style. When publishing mogul Bradford Meade puts his son Daniel in charge of Mode magazine, he hires Betty to be Daniel's new assistant -- mostly because he knows that she may be the only woman in Manhattan with whom the younger man won't sleep.